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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '389549e04764df7b8d08d989a8d6af12af42585df118b50dae91106fb8e60bbc' 
  AND token = 'E7sUvYXgj+5cBwHW7OA9WvNH0gcP6vhc0D8lmmX2iFg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}