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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6169f503b17a48f067609c410608979cf79e0586cdfeada9dd6a9662dfa5b87f' 
  AND token = '0eZrRQWRzX1AQYUpo0iJhMAySMHLpW9t/fkW77+Fegk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}