SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '97b89ebf45cff38c41714fc5e2c93f9516d345f35e9047f5935ffd0c0f336082' 
  AND token = '1zes5Wr1Z2e6uUJWHuvwcDy+KjeP2oj3UFi20t4rRSI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}