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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218de8cdcf94dcabe5c38ffa223592904745140e39068ba26fb29c3c363b46d2' 
  AND token = 'S4rpNWC4xulTO2o2dpzFJrPG++5P0QV0vFIUceZN10E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}