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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8422c18db304eefbf8678d94181a3e384148c8c8cc2b5d977b3500e0a43cacef' 
  AND token = 'fu6EDmzQLa/jQ23LIQ5E4PvvCYRNtyjLWQSFE/MrHos=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}