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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ee2aa11568b1246131d6f5aadaa74d53ba6472a8ce699f600f6c7c94bfd725' 
  AND token = 'me+2H2W0+PrdGCydsf5bUmpj+iJJ1ANAAAll1rKpF14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00058

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}