SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cc887162bb66178becfa41858d8ea97c69ef4b1b851935a526666358663230' 
  AND token = 'oFtHksm0FWjqcKBNwqKMsh8MRc/RwRHrB42ESHgo1RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}