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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a3fe853b95471cd4b055ba25a16cda81f13c621eabf1b979fb03b877054f491' 
  AND token = 'tJW7LarKpHz5KeZtnnQu97HBKtjduVFBU55TM/MjAnA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}