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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c694a4e62eb7b882bd3f998afc20a208ee8b50f0bfd2b0a5e0d4d798466b02c1' 
  AND token = 'JmX1OYXGuyaR7x0UJO7sTT6rLPFLylpitld/PLAwj08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}