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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8d18159867de30c267bdb0762608d2199ffc38da7f962ba5197730bcd149ae2' 
  AND token = 'Uz+7BEvSLhsBGPsg6ydj3KoykMd8xdG0B1ZUdL6d9n4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}