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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ab8defb30a160b5b59bb37e30f03157a92a78cc743b6f5f91c9dbad38591a9b7' 
  AND token = 'DRdYilIHAOc7zTow7vKFC5plVd2I8eB/odRBdG76NKA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}