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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e927f8ab852bb8acc5daa98585dbdd3826b3f21ba57e98190591616d4b6d39d2' 
  AND token = 'LWYN722oVR4t+MFJ6RfWuwzmOTBqtb0fbgYXNiECgMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}