SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e5ea364efd3184bac7b2cb9dc10bccb7da66eb20a8131b88a6af2a8e4bd9615' 
  AND token = '/nGQIIPAguRN2pG8nFJ/DHaDp2y26bHB1ABKOSPHrRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}