SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a53349156617758e102ce13af214debac63de6877306e389678e284418e5012' 
  AND token = 'MZjX/ohLGcF6WvFKEfTpups41yJRBVPRa/0yBo2aNZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}