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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce3f85e221be1ae1434217d5036d8973be4f8c26fdea1e53232794bcf3dd0d97' 
  AND token = 'xL0Xhd/XBl+MaFL3aEWZsxh9Z5KdCA3N4vIsjdIJb5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}