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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '749f3d7eb2c295dff708943a0e360f6eb8f327f4627894120f8c2102c37625cb' 
  AND token = '4K32NlvvmJR97BlLyR4Q+UI9LpbeYWMkV0mBXabLfCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}