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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffbbf00a38da2f920f86d16d4d51e36c5560a52521a505cd9fd153aee3106766' 
  AND token = 'K2zu14T3KbIJb3Sftp1NPQUpZsRLw0CgQ7VkjvLE/6g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}