SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16fd2c9d0cb2a3b7d368e6c8e843c2a0371cc56396b48c33ee78f80bd841d43b' 
  AND token = 'R2QcIHHrpUFSrtbEPCu6Xj7XiZNMfF7hh/bvMW/JkaU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00092

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}