SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60e40e1e9eb04b791f0267f32611481d1fd57f8229b7aa95ca60c0ad0c8f00c4' 
  AND token = 'HGLD8MnuDXOCjh0X5l9obJR8IMdkD2MQWaxGUGEbXdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}