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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15e950aeb08bb3a0e3a2bce0b750d65acd96138f6297cf194d4e5b81a0259bd8' 
  AND token = 'm82aL0z3eoxG3EnLB/9aYgaHQSEyr0jo6zrlH6rT4wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}