SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ead87c484949b221b83b759315fba593009dea7c07b94806858d5e0f20d3fc' 
  AND token = '2Lu6MSz634rL2Bw0n5GQCU025xUip9l2yJsuSa770yQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}