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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce0f42df586adf10c081e2d1b2e7f772e00bd35c6f0b9f2909621928dd4e1d39' 
  AND token = 'D2gGj3003+IXPQPmL8oi+3h36cVBmtIGT2IxAVV9Q70=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}