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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2667ad609c9d38d1a6556fc10bbd8ec4da361754f946b3db55d16f92aaf1a49' 
  AND token = '2sim+yCZPND7RabyG+qLaoSRjMML02Ziy93cx4bTAPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}