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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6220d0aafba09981f0d7841e09549e2a72c3adc04097959260eb2a9b5b71901a' 
  AND token = 'X18WgqNp5prFVmgBdIzDBFYRR9eVi9u0wfkwNIK9/i0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}