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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46cfa33837ed57fc431718547766c00a854117bc104d9fc40f9adbf1792821cb' 
  AND token = 'zILl429se3RkFcs6cOYrmHrg2JTY7EYik29ZKxEYAW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}