SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fba9eae93822226d40bb013e0888382aa0f8de66d53986a1e3f3478480901f4' 
  AND token = '+htB7clucKa/aSCi8lsIDqqSQxnAcvLsUmmYDF+kmj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}