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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ded88e246eb2b7550f59a17cfb873ec76a283bd43590cdb04897c332c610d99' 
  AND token = 'TrQP3qHOFlm34ReVtxHf3+2TmaaN9OIxEq1Jf4buQBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}