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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4ca7d712f647c1ed6dd9cb6cec672a87d69c272d81cb78474deb6545efdd78f' 
  AND token = 'o+WDD1N3Kb5++hXzxev7WhhS6gQKUdBfMXH95z81euU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}