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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b209e3649b1c92f8219bda6548bf802c31159f58513b45ad7bf88477802b404' 
  AND token = 'fRyjTw5jNwe1Vmq+Wn5Nyw8Iegg21vIrr3bI2vxuuk4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}