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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf361c8d0cbaba5cf2326d1b9325d74d19569e0689bc2569697d772d3e3f1468' 
  AND token = 'JPEBePO0tHlqvlJ0L5Tj8mGVP9uXAB+SdcMHOyQk514=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}