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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac2ee0cd65c8f878858769a523139b0853c410f447ee179a033a02a063c5fe6' 
  AND token = 'WuSE8sioz5u+uyESgS5mJYMJUxWwQ26OLuhNhH8Vrw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}