SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc288994e60f62b7dc6fa741e26dbbcb23e3878aec187ecb0a136c596394d58' 
  AND token = 'nJADU6YQgYTcThQM6OYCThmPvJT8ppHzqbQQwdXj23I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}