SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e5c6c31454146e1184a99b61ca4144ca6409fbd89e988c080b7e82bcac01bfe' 
  AND token = 'yTO4fWSWDqnOUQkQq+0O9I/LhdG7AhCE7QfThXqKw88=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}