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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35720532a3cb7c3d8b88a5f15f43d42e8627b1a48a90fb5e5a596aac2d82ecaf' 
  AND token = 'mcAI2p0ZVFbdFTaJlpLyR22CdbebNl8pGvCT9V8hWlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}