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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '758452584c2195466b6f1b9c286ad22515bd277f4b5b8001e22ddc53cad35e90' 
  AND token = 'wZ9WcA+xLfiMCZHhdKyeNF5uQ+LjFgzgAHN6S8wkofw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}