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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e2cde3818be0b0b78d18dc5c1f1cd232d05b6e3e4114164c4d9d1f4fa4cd381' 
  AND token = 'sp/zM0nomPI5lwX1w5qGHXvDWrZTQXQzs8oD7bohwg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}