SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1490563eb580751bd885ac8f6bb56d700e943cd976e5687db60ea02d8df89ca' 
  AND token = 'ZtEALzQW6I8Sx4fNgSdPNnEIpzRFKhLZk5y6PvZAzUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}