SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ad0f20f40cc1fd28adc7460278f111b412003a58a3e743152c55c5dc413c2ce' 
  AND token = 'LMytW/QobHm4hBGzre8dRPVY4yotLdYTv1vf7J6FM2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}