SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e278989ee9f0d7f72a04ba0083691b67808f6fe7db33ab2396f1f4e73db955' 
  AND token = '1+GRLES9ptX8WoL3KT3R1qsM9CWQIlwUA9xB2ATR5NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}