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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565df4c4e25dec2660c51d81c664e28c908b4167e05e0092e7b9c1393d235881' 
  AND token = 'SLn/NY31XehSQf2K4jGYJC6HMqSRmTma1qJ8Y1bT4S8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}