SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '406bc0be9bb5a7932bbb3af314477c649f255be549276274b554485f31b92940' 
  AND token = 'KuGQ0550xb7cpur3GecXonLcbGN7wh1/297cM0vGABY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}