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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e482c2f19f95d49ea979bf8265ae88fd34e5e3cc4a5435748e1a375f9bc406f' 
  AND token = 'YlxBicsL0QBjNK938bjuikwUfmOmedn1kfYgZTpEyRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}