SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22f685bbcb003bf973128f20649bc3564bb1d61731b22686c8c6ca89527b3cba' 
  AND token = 'z4d4xRavRwG0Rlklis3iSzugJrhY/J5v7jIjb1Jhvhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}