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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce24d9bec706ab091912498707c198e5c5d53ce454085c8e406e916917b365dc' 
  AND token = 'tHTb7IaLrpfGrX1tm++mTQBqJsLqu/j5oNV23AoK9aE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}