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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526170d4ef944c77c89bf7d51be38c03d0e65fa3fe3dd77acbd9abb84278611c' 
  AND token = 'DbrNf8+Y5BDgU1GOcB/7+46Jv4x4Vru0UxeB57SzueU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}