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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b0e226dc40e5d9e9040aa0782194de7f2002f17b4385cd8d66ddb366b423fb8' 
  AND token = 'AGSf/BMrsnkqy9XPhhZOEsf/JtSwd1EY0gVHklBy/l0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}