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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed67620d848395e4502c395eb78582b7a2cec3a4c970a04c33688069332ebde' 
  AND token = 'xu93tOrGHQhUKwBdq866zCz6EKguvaEW4dcZ5vsSM8E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}