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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452d86b68c944d541202175f36135ba3f767f487f1bc1653cb08b309478529bb' 
  AND token = 'ARTV0Btliso1eeS8Naga3MgR/B3GcRZhw42M1TrP4jw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}