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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8221533a8d70663fc160d0fbfce098fe0304a8479142beb00adbaeb728fa936' 
  AND token = 'oeP/rwCF2Fknd7X6gmD83cvV3Wb9DiV91FXU4M2OjXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}