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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3eef853edee01544ccf792d42d532c2720f6261cd64e86b6ecdcbbfbb58a3bb' 
  AND token = 'FcQG73I53cxkPMQGyDfvt4/8WMVRRcsnxKbnzH0XZ8o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}